Zyloprim (Allopurinol)

Allopurinol Medication

Generic Allopurinol overview

Allopurinol, also known as Zyloprim, is a drug of the list of the Essential Medicines, composed by WTO, and it is considered one of the most important drugs of the basic health system. This xanthine oxidase inhibitor works by reducing the purine synthesis, and thus lowering uric acid levels in blood. High levels of uric acid cause various diseases, such as chronic gout, inflammatory bowel disease, tumor lysis syndrome, kidney stones and other health problems. The Allopurinol 300 mg is well known as a widely used solution for chronic gout since 1966. As the patent has expired, a number of generic Allopurinol drugs have been introduced: Progout, Allosig, Zyloric, Aluron and, of course, Zyloprim. Most of them are available for sale online: you can buy Zyloprim 300 mg without prescription in the online pharmacy.

Allopurinol medication usage

People buy Allopurinol online no prescription pharmacy in order to treat many various health conditions: from gout and hyperuricemia to epilepsy and reperfusion injury. However, most common usages of the Allopurinol medication are gout, inflammatory bowel disease, and tumor lysis syndrome. In patients with chronic gout, for example, this medication prevents future attacks of the disease; nevertheless, it cannot help in case such attacks have occurred. For inflammatory bowel disease, it is not enough to simply buy Allopurinol 300 mg online without prescription: the drug is used in cotherapy with thiopurine. In this case, the initial dose of the medication is reduced to 1/3, and Zyloprim is taken in addition to it, enhancing the effect.

Mechanism of action

Zyloprim works by inhibiting the xanthine oxidase enzyme. The drug is a natural analogue of purine, synthesized in the body, and it prevents the breakdown of incoming purine into uric acid. Particularly xanthine oxidase is responsible for production of uric acid, and inhibiting this enzyme, Zyloprim prevents the excessive output of the process that leads to high levels of uric acid in blood. Intake of Zyloprim reduces the uric acid blood levels, which is essential to prevent gout attacks, and many other problems.

Allopurinol without prescription: precautions and contraindications

Before you attempt to make Allopurinol buy online without prescriptions, you have to familiarize with the precautions and contraindications, as well as receive help in individual dose adjustment, to make your treatment safe and effective. One of the most important things that you have to know about Allopurinol is that it requires precise dose definition, set by medical specialist, and regular monitoring of the state of the patient. Though there are not many contraindications to the administering of this drug, patients with hypotension, allergic reactions to the drug components and other intolerances, should not take Zyloprim. If you do not know how much Allopurinol I can take for gout, you should consult your doctor on this matter.

Zyloprim 300 mg side effects

One of the reasons for manifestation of Zyloprim 300 mg side effects is problematic dosage of this medication. It requires very precise individual adjustment, otherwise leads to serious side effects. One of the most often adverse effect of Zyloprim is skin rash, which usually results in discontinuation of the therapy. Other complications may show as cytopenias, or aplastic anemia. Rarely patients report peripheral neuritis, or interstitial nephritis. The most serious problem is possibly lethal dermatological conditions: Stevens-Johnson syndrome, or toxic epidermal necrolysis, both of which may become life threatening.

Where to buy Allopurinol no prescription UK

Despite the potential risk of improper dose, Allopurinol (Zyloprim) is available online without prescription. When you attempt to buy Allopurinol online no prescription UK, you should understand the risks and consult your doctor timely. Generic Allopurinol is equal in compound, efficiency and safety to the brand drugs, so there is no reason to overpay for it, buying it from local drug stores. It is cheaper and more convenient to choose online Allopurinol pharmacy for such purchase.


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